Felipedia

© Some material sourced from Rand, J (2006) Problem-based feline medicine. Saunders Elsevier, Sydney

Drug	Indications	Dose	Route	Frequency
Acarbose	Hyperglycaemia	12.5 - 20 mg	Oral	with each meal
Acemannan (Aloe vera derivative)	Immunomodulation	1-2 mg/kg	Intralesional, IP or SQ	weekly
Acepromazine (ACP)	Sedation, restraint	0.05-2.25 mg/kg	SQ, IM, PO	q 8-12hrs
	Arterial thromboembolism	0.15-0.3 mg/kg	SQ	q 8-12hrs
	Amphetamine toxicosis	0.05 -1.0 mg/kg	IV, IM, SQ	q 8-12hrs
Acetazolamide	Glaucoma	5-10 mg/kg	PO	q 8-12hrs
Acetylcysteine	Mucolytic and acetaminophen toxicity	140 mg/kg	IV	loading dose
		70 mg/kg	PO	4-6 x 5-7 treatments
Acetylsalicylic acid (Aspirin)	Antipyretic	6-10 mg/kg	PO	q 48 - 72hrs
	Antithrombotic	80 mg/cat or 25 mg/kg	PO	2 times/wk
	Anti-inflammatory	10-20 mg/kg	PO	q 48 hrs
	Analgesia	10 mg/kg	PO	q 48hrs
Actinomycin-D	Anticancer / antimicrobial	0.5-0.9 mg/m²	IV	once every 3 weeks
Acyclovir	Anti-herpes viral	200 mg	PO	q 6hrs
S-Adenosylmethionine (SAME)	Replenishes glutathione stores in chronic liver disease	20-30 mg/kg	PO	q 24hrs
Albendazole	Lung worm	50 mg/kg	PO	daily for 21 days
Albuterol (Salbutamol)	Bronchodilation		PO	q 6 - 8hrs
Allopurinol	Urate urolithiasis	10 mg/kg	PO	q 8 - 12hrs for 30 days
Alprazolam (Benzodiazepine)	Elimination behavioural problems	0.125-0.25 mg/cat	PO	q 12hrs
Aluminium carbonate gel	Phosphate binder	10-30 mg/kg	PO with meals	q 8hrs
Aluminium hydroxide	Antacid	20-30 ml	PO	q 2 - 4hrs
	Phosphate binder	30-90 mg/kg	PO with meals	q 8 - 24hrs
Amantadine	Analgesia for chronic pain	3-5 mg/kg	PO	daily for 7-14 days
Amikacin	Susceptible infections	15-22 mg/kg	IM, IV, SQ	q 24hrs
Aminopentamide (Centrine)	Antidiarrheal	0.1 mg/cat	SC, IM, PO	q 8 - 12hrs
Aminophylline	Bronchodilator	4-6.6 mg/kg	PO	q 8 - 12hrs
		2-5 mg/kg	IV infusion	q 12hrs
Aminopromazine	Smooth muscle relaxant	2.0-4.5 mg/kg	PO	q 12hrs
6-aminosalicylic acid	Irritable bowel syndrome	see mesalamine, olsalazine
Amitriptyline (Endep-10)	Behaviour, urine spraying	2 mg/kg or 5-10 mg/cat	PO	q 24hrs
Amlodipine besylate (Norvasc)	Systemic hypertension	0.625 mg/cat	PO	q 24hrs
Ammonium chloride	Struvite dissolution	800 mg/cat	PO	q 24hrs
Amoxicillin/clavulanic acid	Susceptible infections	10-20 mg/kg	PO	q 12hrs
Amoxil (Amoxicillin)	Susceptible infections	4-11 mg/kg	PO	q 12hrs
Amphetamine sulphate	CNS stimulation during certain toxicoses	5 mg/cat	PO	q 12hrs
Amphotericin B	Systemic mycoses	0.15-1 mg/kg in 5% dextrose	IV	q 48hrs to a total cumulative dose of 10mg/kg
			SQ	diluted 1:10 in saline
Ampicillin	Susceptible infections	20-60 mg/kg	PO	q 8 - 12hrs
Amprolium	Coccidiosis	60-100 mg/kg	PO	q 24hrs x 5 d
	With sulfadimethoxine	150 mg/kg	PO	q 24hrs x 5d
Aprotonin	Protease inhibitor (pancreatitis), fibrinolytic agent	5000 KUI (kallikrein inhibitor units)/kg	IP	q 6 - 8hrs
Ascorbic acid (Vitamin C)	Feline infectious peritonitis	25-125 mg/kg/day	PO	q 24hrs
	Acetaminophen toxicosis	30 mg/kg	PO, SQ	6x7 treatments
Asparaginase	Lymphosarcoma	10,000 U/m²	IV	weekly as part of a protocol
Atenolol (Tenormin)	ß₁-blocker for HCM + hypertension	6.25 mg/cat	PO	q 24hrs
Atipamezole (Antisedan)	Medetomidine reversal	equivolume	IM	as needed
Atovaquone	Antiprotozoal (pneumocystosis)	13.3 mg/kg with fatty meal	PO	q 8hrs x 21 days
Atracurium besylate	Paralytic anaesthetic agent	0.1-0.25 mg/kg	IV	repeated q 30mins
Atropine	Sinus bradycardia	0.02-0.04 mg/kg	IM, IV, SQ	as required
	Organophosphate toxicity	0.2-2.0 mg/kg	IM, SQ	q 2hrs
Aurothioglucose	Pemphigus complex, LPS, and podomatitis	2 mg	IM	stat, then 1 mg/kg weekly
Azathioprine	Enteritis	0.2-0.3 mg/kg	PO	q 24-48hrs
	Immune haemolytic anaemia	1 mg/kg	PO	q 24-48hrs
	Immunosuppression	1.1 mg/kg	PO	q 48hrs
Azithromycin (Zithromax)	Susceptible infections	5 mg/kg	PO	q 24 - 48hrs
	Susceptible infections	80 mg stat	PO	weekly x 3
Aztreonam	Susceptible infections	12-25 mg/kg	IV, IM	q 8-12hrs
Baquiloprim	Coccidiosis	30 mg/kg	PO	q 48hrs x 2
Baytril	Susceptible infections	5.0-20.0 mg/kg	PO, SQ, IM, IV (with caution - may cause blindness)	q 24hrsfor 7-10 days
Beclomethasone dipropionate	Anti-inflammatory	200 mg	Inhalant	as required
Benazepril (Fortekor)	Afterload reduction (Renal, CHF)	0.25-0.5 mg/kg	PO	q 24hrs
Benzimidazole	Trypanosomiasis	5 mg/kg	PO	q 24hrs for 4 months
Benzocaine	Local anaesthetic	1-5 ml	SQ	as required
Benzoyl peroxide	Seborrheic, antibacterial	leave on skin for 10mins		q 3 - 4days for 2 weeks
Betamethasone	Anti-inflammatory	0.1-0.2 mg/kg	PO	q 12 - 24hrs
Bethanechol	Bladder atony, dysautonia	1.25-5.0 mg	PO	q 8- 12hrs
Bisacodyl	Stool softener	2-5 mg/cat	PO	q 24hrs as needed
Bismuth subcarbonate	GI tract protectant	0.3-3.0 gm	PO	q 4hrs
	Antidiarrheal, antiemetic	1-3 ml/kg	PO	q 4 - 6hrs
Bleomycin	Chemotherapy	10 µg/m²	IV, SQ	q 24hrs for 4 days, then weekly; max dose 200mg/m²
Bran	Stool softener	1-2 teaspoons/400g food	PO	as needed
Brewer's yeast	B vitamin source	0.2 µg	PO	q 24hrs
Bromide, Potassium	Anticonvulsant	30-60 mg/kg	PO	q 12hrs
Bromocriptine mesylate	Cushing's syndrome, false pregnancy, lactation cessation	10-30 µg/kg	PO	q 24hrs for 10 -16 days
Bunamidine	Taenia, Dipylidium	20-50 mg/kg	PO	after 3hr fast
Bupivicaine hydrochloride	Local Anaesthetic	0.22-3.0 ml/cat	Epidural	stat
Buprenorphine	Opioid analgesic	0.005-0.01 mg/kg	IV, IM	q 4-8hrs
Buspirone (Clomicalm)	Behavioural therapy	2.5-5.0mh/cat	PO	q12-24hrs
Busulfan	Chronic myelocytic leukaemia	3-4mg/m2 or 0.1 mg/kg	PO	q 24hrs
Butamisole	Hookworm, whipworm	2.2mg/kg	SQ	q 21days
Butorphanol	Preanaesthetic	0.05-0.4mg/kg with ACP	IV, IM, SQ
	Antiemetic	0.2-0.6mg/kg	SQ, IM, IV
	Analgesia	0.1-0.8 mg/kg	PO	q 6 - 12hrs
Calcitriol	Hypoparathyroidism, renal secondary hyperparathyroidism	1.5 - 3.0 ng/kg	PO	q 24hrs
Calcium carbonate	Nutritional supplement	1/2 tsp	PO	daily
	Phosphate binder	60-100 mg/kg	PO	daily
Calcium chloride 10%	Ventricular asystole	1 ml/9kg or 0.1-0.3ml/kg	IV (slowly)	stat
	Hypocalcaemia	1 ml/9kg	IV	stat
Calcium citrate	Calcium replacement, urolithiasis	10-30 mg/kg	PO	q 8hrs
Calcium EDTA	Lead poisoning	100 mg/kg/day	SQ	daily for 5 days
Calcium gluconate	Ventricular asystole	0.5-1.5 ml/kg	IV (slowly)	as required
	Hypocalcaemia, hyperkalemia	0.5-1.5 ml/kg	IV (slowly)	as required
Captan powder 50%	Dermatomycoses	2 tablespoons/gal water	topically, do not rinse	2-3 x week
Captopril	Vasodilator	2-3 mg/cat	PO	q 8-12hrs
		3-6.25 mg/cat	PO	q 12hrs
Carbenicillin	Susceptible infections	15-30 mg/kg	IV	q 8hrs
Carbenicillin indanyl sodium	Urinary tract infections	10-55 mg/kg	PO	q 8hrs
Carbimazole	Hyperthyroidism	5 mg/cat	PO	q 8 - 12hrs
Carboplatin	Chemotherapy	200 mg/m²	IV	q 4weeks
Carmustine	Chemotherapy	50 mg/m²	IV	q 6weeks
Carprofen (Rimadyl)	Analgesic	1-4 mg/kg	SQ	stat
		0.5-1.0 mg/kg	PO	q 24hrs
Cefadroxil (Cefa-drops - cephalosporin)	Susceptible infections	50 mg/cat	PO	q 24hrs for 1-4 weeks
Cephalexin (Rilexin)	Susceptible infections	10-35 mg/kg	PO	q 8 - 12hrs
Cetacaine	Topical anaesthetic	Use cautiously	Topical	May cause methaemaglobinaemia
Charcoal, activated	Adsorbent for poisonings	1-8g/kg	PO	as needed
Chlorambucil	Chemotherapy	0.1-0.5mg/kg	PO	q 48-72hrs
	Immune mediated skin disease	0.1-0.2mg/kg	PO	q 48hrs with prednisolone
Chloramphenicol	Susceptible infections	50mg/cat	PO	q 12hrs
Chlordiazepoxide-clidinium (Benzodiazepine)	Irritable bowel syndrome	1-2 tabs	PO	q 12hrs
Chlorhexidine 0.5%	Burns	dilute 1:40 with saline	topically	q 24hrs
Chlorothiazide	Diuretic	10-40 mg/kg	PO	q12hrs
	Partial ADH deficiency	20-40 mg/kg	PO	q12hrs
Chlorpheniramine	Antihistamine	1-2 mg/cat	PO	q 8-12hrs
	Excessive grooming	2-4 mg/cat	PO	q 12-24hrs
	Antiemetic	0.5 mg/kg	IM	q 6-8hrs
Chlortetracycline hydrochloride	Susceptible infections	25 mg/kg	PO	q 6-8hrs
Cholecalciferol (Vit D)	Hypocalcaemia	500-2000 U/kg	PO	q 24hrs
Cimetidine	Esophagitis, gastric ulceration, antiemetic, chronic gastritis	5-15 mg/kg	PO, IV, IM	q 8 -12hrs
	Immunomodulator	10-25 mg/kg	IV, IM, PO	q 12hrs
Ciprofloxacin	not bioavailable in cats
Cisapride (Prepulsid)	Chronic constipation, megacolon	0.5-5.0mg/cat	PO	q 12hrs
Clarithromycin	Atypical mycobacterial	50 mg/cat	PO	q 12hrs
Clavulox (Amoxicillin / Clavulanic acid)	Susceptible infections	10-20 mg/kg	PO	q 12hrs
Clindamycin	Anaerobic infections	5-11 mg/kg	PO	q 12hrs
	Stomatitis, acute pancreatitis	22 mg/kg	PO	q 24hrs
	Pancreatic exocrine insufficiency	5-10 mg/kg	PO	q 6 - 8hrs
	Enteroepithelial cycle	12.5-50 mg/kg	PO	q 12hrs
Clofazimine	Feline leprosy	4-8 mg/kg	PO	q 24hrs for 6 weeks
		50 ng/cat	PO	q 48hrs
Clomipramine	Behaviour modification	1-5 mg/cat	PO	q 12 - 24hrs
Clonazepam (Benzodiazepine)	Anticonvulsant, behaviour therapy	0.5 mg/kg	PO	q 8-12hrs
Clorazepate (Benzodiazepine)	Anxiolytic drug	1-2 mg/kg	PO	q 8 - 12hrs
Clotrimazole	Dermatophytosis	apply to lesion	topical	q 12hrs
	Antifungal	60 ml of 1 g/dl of polyethylene glycol intranasal		over 1 hr under general anaesthesia
Cloxacillin	Susceptible infections	20-40 mg/kg	PO, IM, IV	q 4 - 8hrs
Coal tar shampoos	Seborrhoea	Keep in contact with skin for 10 mins	Topically	q 24hrs
Cobalamin	see Vit B12
Cod liver oil		1 teaspoon / 10 kg
Codeine	Pain relief	0.5-4 mg/kg	PO	q 6 - 12hrs
	Antitussive, analgesia	0.1-0.3 mg/kg	PO	q 4 - 6hrs
Colchicine	Antifibrotic	0.01-0.3 mg/kg	PO	q 4 - 6hrs
Colony stimulating factor	Neutropenia	2.5-5.0 mg/kg	SQ	q 24hrs
Corticotrophin gel (ACTH)	Response test	pre-ACTH sample 0.5-2.2 IU/kg	IM
Cortisone acetate	Hypoadrenocorticism ( Addison's)	1 mg/kg	PO, IM	q 24hrs
Cosequin^®	Osteoarthritis	1 capsule	PO	q 24hrs
Cosyntropin	pre-ACTH sample	0.125 mg/cat	IV
		1-2 mg/kg	PO (with caution)	q 12hrs x 2
Cromolyn sodium 4% (Cromone)	Allergic conjunctivitis		Topically	q 4 - 6hrs
Cyanocobalamin	Vit B₁₂ deficiency	50-1000 µg	PO, IM, SQ	q 24hrs
Cyclizine	Antiemetic	4 mg/kg	IM	q 8hrs
Cyclophosphamide	Anticancer	100 mg/m²	IV
	Feline mammary cancer	100 mg/m²	PO	q 3 weeks with doxorubicin
	Immune haemolytic anaemia	2 mg/kg (50mg/m²)	PO	q 24hrs for 4 days per week
	Lymphosarcoma, myeloproliferative disorders	50 mg/m²	PO	q 48hrs
	Autoimmune skin disease, SLE	50 mg/m²	PO	q 24hrs 4 days/wk or q 48hrs
	Multiple myeloma	7 mg/kg	PO	once
	FIP	2-4 mg/kg	PO	q 24hrs 4 days a week
	Eosinophilic enteritis	6.6 mg/kg	PO	q 3days then q 24hrs
		2.2 mg/kg	PO	q 24hrs
	Immunosuppressive therapy	2.2 mg/kg (6.25-12.5 mg/cat)	PO	q 48hrs or q 24hrs for 4 days a week
Cyclosporin	Immune-mediated thrombocytopenia, SLE, sebaceous adenitis	4-6 mg/kg	4hr IV infusion	q 24hrs (avoid extravasation)
		3-7 mg/kg	PO	q 12hrs
		10 mg/kg	PO	q 12hrs
Cyclosporine ophthalmic	Keratoconjunctivitis sicca, pigmentary keratitis plasmoma of third eyelid	1-2% solution	drop in eye	q 12hrs
Cyclothiazide	Diuretic	0.5-1.0 mg/kg	PO	q 24hrs
Cyproheptadine	Appetite stimulant	1-4 mg/cat	PO	q 12 - 24hrs
Cytarabine	Anticancer	30-50 mg/kg	IV, IM, SQ	once a week
		100 mg/m²	IV. IM, SQ	q 24hrs for 4 days then
		20 mg/m²	Intrathecal	q 24hrs for 1 - 5 days
Cythioate	Tick prevention	1.5-3.3 mg/kg	PO (tab)	q 72hrs or 2 x week
		0.22 ml/kg	PO (liquid)	q 72hrs or 2 x week
Dacarbazine	Lymphoreticular neoplasms	200-250 mg/m²	IV	q 24hrs for 5 days, every 21 days
	Soft tissue sarcomas	1000 mg/m²	IV infusion	over 6 - 8hrs, every 21 days
Dactinomycin (Actinomycin-D)	Anticancer	0.015 mg/kg	IV	q 24hrs for 3 - 5 days, wait 3 weeks then
		0.7-1.5 mg/m²	IV	weekly
Dalteparin (low MW heparin)	DIC, thrombosis	70 IU/kg	SQ	q 24hrs
Danazolol	Immune-mediated disorders	5-10 mg/kg	PO	q 12hrs
Dapsone	Mycobacteriosis	1.1 mg/kg	PO	q 12hrs for 4-6 weeks
	Brown recluse spider bite	0.7-1.0 mg/kg	PO	q 8hrs
Decatibine (Dacogen)	Anticancer; chronic lymphocytic leukaemia (methylation inhibitor)	400-800 mg/m²	IV, SQ	q 24hrs x 10
Deferoxamine mesylate	Iron chelator	10 mg/kg	IV, IM, SQ	q 2hrs for 2 doses then q 8hrs for 24 hrs
	Repertusion (ischaemia) injuries	50 mg/kg	IV	over 5 mins
Demeclocycline	Inappropriate ADH secretion	3-12 mg/kg	PO	q 6 - 12 hrs
Deprenyl (Fitergol)	Hyperadrenocorticism, cognitive dysfunction	see Selegiline
Derm caps	Skin disorders	1 capsule per 9kg	PO	q 24hrs
Desmopressin acetate	Central diabetes insipidus	0.3 µg/kg	IM	q 12 - 24hrs
Desoxycorticosterone acetate	Hypoadrenocorticism	0.2-0.4 mg/kg	conjunctivally	q 24hrs, max 5mg
Desoxycorticosterone pivalate	Hypoadrenocorticism	25 mg	IM	stat
Dexamethasone	Central oedema, spinal cord trauma, DJD, other CNS trauma	2 mg/kg	IV	then,
		1 mg/kg	IV, SQ	q 8-12hrs, then
		0.1 mg/kg	IV, SQ, PO	q 8-12hrs
	Hydrocephalus	0.25 mg/kg	IV, IM, PO	q 6 - 8hrs
	Shock, anaphylaxis	4 - 6 mg/kg	IV (slowly)
	Immune-mediated disease	0.25-1.25 mg/kg	PO	q 12 - 24hrs
		0.1-0.15 mg/kg	SQ, PO	q 12hrs for 5 - 7 days, then taper dose
	Adrenocorticoid collapse	0.1-0.5 mg/kg	SQ, IV	with mineralocorticoids
	Feline bronchial asthma	1 mg/kg	IV	then
		0.25-1.0 mg/cat	PO	q 8 - 24hrs
Dexrazoxane	Iron chelation for doxorubicin-induced cardiotoxicity	25 mg/kg (ratio of 10-20:1 dexrazoxane : doxorubicin)	IV	15 mins before doxorubicin
Dextran 40	Shock	10-20 ml/kg	IV	q 24hrs
Dextran 70	Volume expander	10-20 ml/kg	IV	q 24hrs to effect
Dextroamfetamine